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Google recently updated the way search results display when a user searches for a medication, including brand names, generic/compound names and OTC products (see “Naproxen,” right). When a user searches by a medication name, a revamped version of Google’s Knowledge Graph information box now appears alongside regular search results.

Revamped version of Google’s Knowledge Graph information box

  • Although the Knowledge Graph has been appearing in search results for some time, Google recently updated its design to be more appealing and interactive, and content is aggregated from various sources.
  • The new design mirrors the design Google rolled out last February for disease-condition searches.

An Intouch Solutions analysis showed two issues of concern:

  • Content featured in these boxes continues to evolve and is not always consistent or completely accurate.
  • The update could negatively affect click-thru rates for branded product websites for certain search terms.

This POV provides information on the updated Knowledge Graph boxes and the implications for those involved in the promotion of medications online.


Knowledge Graphs have been appearing in search results for a variety of queries since mid-2012. Google previously used different designs for health condition searches than it did for medication searches, but in December 2015, it switched to one format for both search types:

Comparison of old and new knowledge graph results

List of info included in updated knowledge graph for drug searchesSO WHAT’S IN THE UPDATED KNOWLEDGE GRAPH BOX?

  • Generic name (with option to hear pronunciation)
  • Brand name or list of common brand names
  • Drug class
  • Controlled substance warning (where applicable)
  • links to side effects, interactions and warnings
  • (by administration type, if applicable)
  • Availability, i.e., if a prescription is needed
  • Pregnancy and alcohol safety considerations
  • Indications it may treat (where applicable)
  • Related medications


Not all medication searches result in the updated Knowledge Graph information box.

  • Before the December 2015 rollout, some medication searches resulted in the 2012 version of Knowledge Graph, while others had none at all.
  • Those with no Knowledge Graph before the rollout have continued without one.
  • Of the brands Intouch reviewed, 80% of those with the 2012 version of the box have transitioned to the new version, which suggests this is a permanent changeover as opposed to a test.

NOTE: In order to receive either type of Knowledge Graph (original or revamped) in results, searches must contain only the brand or generic drug name in the query. No other words can be included. For example, “naproxen” triggers a Knowledge Graph box, but queries like “naproxen dosing” or “can naproxen be taken with other medications” or “naproxen side effects” do not.


One key difference between results displayed for a health condition Knowledge Graph box versus those displayed for a medication is the source of the content (shown at the bottom of the box at right). The content for health conditions is compiled, curated and reviewed by a team of doctors and then checked by the Mayo Clinic. However, it appears that content for the revamped medication Knowledge Graph is aggregated from sites such as the U.S. Food and Drug Administration, U.S. National Library of Medicine, Mayo Clinic, DailyMed, Micromedex, and “others.”

This is similar to the way that other, non-medical Knowledge Graphs are populated. For example, content that appears from a search for musician
Bob Dylan is a mixture of magazine articles, Wikipedia entries, Facebook fan pages and other “unofficial” sources — meaning the information could have been written without rigorous oversight.

Google provides a feedback box in the bottom-right corner of the Knowledge Graph for reporting problems with content. If the feedback option is not visible, the “More about this information” dropdown link can be clicked. There is also an option to request removal based on legal grounds.

NOTE: While all Google users have the ability to submit feedback, employees working in the pharmaceutical industry are encouraged to adhere to their own standard operating procedures regarding correction of misinformation on the Web.


Because one in 20 Google searches is for health-related information, many speculate the health-related Knowledge Graph is Google’s ongoing effort to capture and keep the large volume of health-related searches on Google-related properties. If a healthcare provider, for example, is simply confirming the spelling of the generic name for a branded product, the box will tell them what they need to know without clicking through to a branded site.

As the revamped Knowledge Graph is designed to be more interactive and aesthetically pleasing, Intouch investigated whether the change was lowering organic click-thru rates in the search results. Intouch reviewed 26 brands across various pharmaceutical companies and estimated the new medication Knowledge Graph reduced organic click-thru rates to the websites by just over 4% on average.

  • Twelve of the 26 branded sites had no Knowledge Graph for their brand or generic term. This cohort acted as the control, and their average click-thru rate change from the week before the rollout to the week after was 0.01%.
  • However, for the 14 sites that changed from the old Knowledge Graph to the new one, the average click-thru rate change was -4.36% over the same timeframe.

While these results are not statistically significant, Intouch is reasonably confident in its conclusion: The new Knowledge Graph results in a slight negative impact on organic traffic. It is probable that pay-per-click is also negatively affected.


All brands should review their Knowledge Graph results to understand what content appears in search results. Due to concerns about the responsibility of pharmaceutical companies to correct inaccurate information found online, careful judgement should be used, referencing your company’s own standard operating procedure. Submitting feedback to Google or the original source does not guarantee they will make a change, but it certainly increases the chances. And since content changed even over the course of developing this POV, Knowledge Graph result audits should be conducted on a regular basis.

Considering Knowledge Graph boxes may have slightly negative impacts on website traffic —and because only root branded and generic terms are triggering them — Intouch recommends seeking out and taking advantage of opportunities to optimize for long-tail branded traffic
(e.g., “can Advil be taken with other medications”). Long-tail keywords are defined as any search queries consisting of four or more words. They generally have more identifiable search intent, are searched fewer times and are easier to rank for organically. Intouch consistently recommends attention to long-tail traffic for a variety of reasons — helping to fulfill specific user needs, increasing organic ranking likelihood, etc. — and this new information reinforces its importance. Now may be a good time to review and update your brand’s paid search marketing strategy as well.

If you have questions about updates to Knowledge Graph, please reach out to your Intouch contact for more information.